Dr. Guarné's research interests are focused in understanding how architectural proteins determine the fate of DNA in chromosome replication and repair. Since most of the proteins that regulate these processes lack a measurable enzymatic activity, our efforts are aimed at seeing how these proteins interact with DNA. We use a broad range of structural biology techniques that we combine with molecular biology, biochemical and genetic analysis to characterize how the structure of these complexes determines their function.
If you want to learn more about our current projects, please visit our Research page or check the Publications by members of the lab.
If you are interested in a position at the Guarné lab please contact us by e-mail.